PREDICTIVE MARKERS OF THE DEVELOPMENT OF GESTATIONAL COMPLICATIONS AND THE RESULT OF PREGNANCY IN WOMEN WITH PHYSIOLOGICAL AND COMPLICATED COURSE OF PREGNANCY
Keywords:
biochemical markers, premature birth, gestational complications, hormonal statusAbstract
The aim of the study: to determine the predictive markers of gestational complications and adverse pregnancy outcomes. A comprehensive clinical and laboratory examination of 83 pregnant women (41 - with the physiological course of the gestational period and urgent childbirth, 42 - with premature birth and antenatal fetal death) aged 20 to 45 years old was carried out.
All women underwent a general clinical examination, hemodynamic studies in the "mother-placenta-fetus" system, hormonal function of the placental complex, as well as levels of biochemical markers.
It was found that the somatic and gynecological anamnesis of pregnant women of the examined groups did not differ significantly. In women with a complicated course of the gestational period and an unfavorable pregnancy outcome in the early stages of the perinatal period, there is a deterioration in clinical and biochemical blood tests, biochemical markers and Doppler measurements. Since most of the studied indicators of pregnant women of the second group are within normal range, although they are significantly worse than in women of the first group, and their direct examination by a doctor does not suspect possible premature termination of pregnancy, the development of models for predicting the course and pregnancy outcome is urgent. This will make it possible to form a risk group for premature birth, carry out early prevention and appropriate treatment of women and prevent perinatal losses.
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