NEODJUVANT THERAPY IN THE TREATMENT OF RECTAL CANCER

Abstract

Rectal cancer (RC) is an urgent problem in oncology. This is due to high morbidity and mortality rates worldwide. Treatment of RPC is being improved every year, new methods of drug, radiation and surgical therapy are being introduced. In this regard, neoadjuvant chemo-radiation therapy of RPC is of great interest. Many aspects of this treatment method have not yet been developed. The Kazakh Research Institute of Oncology and Radiology conducted a study on the effect of neoadjuvant therapy in 146 patients with PKK. Three groups of patients were analyzed: 1) those who received preoperative chemo-radiation therapy with subsequent surgery; 2) those who received chemo-radiation therapy without surgery; and 3) those who received only surgical treatment. Neoadjuvant chemo-radiation therapy improves the clinical symptoms of the disease and creates favorable conditions for performing radical operations.