MORPHOLOGICAL FEATURES OF CRYPTOCOCCOSIS DEVELOPMENT IN THORAX ORGANS AT PATIENTS WITH VARYING DEGREES OF IMMUNODEFICIENCY

Authors

  • S. Kuzovkova SO “National institute of phthisiology and pulmonology named after F. G. Yanovsky NAMS of Ukraine”, Kiev
  • I. Liskina SO «National institute of phthisiology and pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine», Kiev
  • L. Zagaba SO «National institute of phthisiology and pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine», Kiev
  • O. Melnyk SO «National institute of phthisiology and pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine», Kiev

Keywords:

cryptococcosis, fungus morphology, thorax organs, tissue reaction, immunodeficiency.

Abstract

The paper presents the results of a study of morphological signs of the mycosis development in thorax organs caused by cryptococcus in patients with various degrees of immunosuppression. The presence, number and localization of fungal cells, their morphological features, as well as the nature and severity of the inflammatory cellular reaction in the tissue of the lungs, pleura and lymph node were studied. It has been shown that the morphological picture in cryptococcal lesions of the thorax organs is represented by fairly diverse morphological changes, which is associated with both different virulence of the fungus and with a different degree of immunodeficiency and the duration of the pathological process. Mostly there are alterative and productivenecrotic granulomatous types of inflammatory response. With complete suppression of immunity, there may be a lack of tissue reaction.

Author Biographies

S. Kuzovkova, SO “National institute of phthisiology and pulmonology named after F. G. Yanovsky NAMS of Ukraine”, Kiev

Candidate of medical Sciences, senior researcher of the laboratory of pathomorphology

I. Liskina , SO «National institute of phthisiology and pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine», Kiev

Doctor of Medical Science, senior researcher, the Head of the laboratory of pathomorphology

L. Zagaba , SO «National institute of phthisiology and pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine», Kiev

Candidate of medical Sciences, researcher of the laboratory of pathomorphology

O. Melnyk , SO «National institute of phthisiology and pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine», Kiev

Candidate of biological Sciences, junior researcher of the laboratory of pathomorphology

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Published

2021-03-23

Issue

Vol. 1 No. 1(65) (2021)

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