THE INTERRELATION OF CYP2C9, CYP4F2, VKORC1 GENES POLYMORPHISMS WITH WARFARIN DOSE AND HEMORRHAGIC COMPLICATIONS RISK RISE IN PATIENTS WITH ATRIAL FIBRILLATION: A RETROSPECTIVE STUDY

Authors

  • M. Kolesnyk Zaporizhzhia State Medical University
  • Y. Mykhailovskyi Zaporizhzhia State Medical University

Keywords:

atrial fibrillation, warfarin, dosing, genes, bleeding.

Abstract

The aim of the study was to identify the frequency of CYP2C9, CYP4F2, VKORC1 genes polymorphisms in patients with atrial fibrillation (AF) and to establish their interrelationship with warfarin (WF) dose and the hemorrhagic complications risk rise.

Author Biographies

M. Kolesnyk, Zaporizhzhia State Medical University

MD, PhD, DSci, Professor, Professor of the Department of Family Medicine, Therapy, Cardiology and Neurology of Faculty of Postgraduate Education

Y. Mykhailovskyi , Zaporizhzhia State Medical University

PhD student at the Department of Family Medicine, Therapy, Cardiology and Neurology of Faculty of Postgraduate Education

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Published

2021-03-23

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