THE IMPORTANCE OF COMPRESSION SONOELASTOGRAPHY IN IMPROVING THE DIAGNOSTICS OF THE PATHOLOGY OF MYOMETRY
Keywords:
adenomyosis, leiomyoma, compression sonoelastographyAbstract
We carried out a comparative clinical assessment of the possibility of compression sonoelastography with the data of histological examination in the process of diagnosing myometrial pathology. 155 women were examined, the average age of which was 44 ± 3.6. Elastographic images of adenomyosis and leiomyoma were analyzed in those patients in whom the elastographic diagnosis was confirmed by histological examination. Group 1 included 30 women with leiomyoma, group 2 consisted of 14 women with suspected adenomyosis, group 3 (42 women) - combined pathology of adenomyosis and leiomyoma. Leiomyoma and adenomyosis had different elastographic characteristics (strain ratios) with different color mapping; their specific characteristics and main differences are determined. Based on sonoelastography, the majority of patients (n = 30) were suspected of having uterine fibroids, 14 had adenomyosis, and 42 had adenomyosis and fibroids. In 3 patients with uterine leiomyoma in sonoelastography revealed histological signs of adenomyosis. Compression sonoelastography is able to identify clear distinguishing features of leiomyoma and adenomyosis, and consistency of diagnoses based on sonoelastography and histology is significant but not optimal.
References
Graziano A, Monte, GL, Piva I, Caserta D, Karner M, Engl B, et al. Diagnostic findings in adenomyosis: A pictorial review on the major concerns. Eur. Rev. Med. Pharmacol. Sci. 2015; 19: 1146-1154.
Harada T, Khine YM, Kaponis A, Nikellis T, Decavalas G, Taniguchi F. The Impact of Adenomyosis on Women's Fertility. Obstet. Gynecol. Surv. 2016; 71: 557-568. https://doi: 10.1097/OGX.0000000000000346
Li JJ, Chung JP, Wang S, Li TC, DuanH. The Investigation and Management of Adenomyosis in Women Who Wish to Improve or Preserve Fertility. BioMed Res. Int. 2018; 2018: 6832685. https://doi: 10.1155/2018/6832685
Eisenberg VH, Arbib N, Schiff E, Goldenberg M, Seidman DS, Soriano D. Sonographic Signs of Adenomyosis Are Prevalent in Women Undergoing Surgery for Endometriosis and May Suggest a Higher Risk of Infertility. BioMed Res. Int. 2017; 2017: 8967803. https://doi: 10.1155/2017/8967803
Abbott JA. Adenomyosis and Abnormal Uterine Bleeding (AUB-A)-Pathogenesis, diagnosis, and management. Best Pract Res Clin Obstet Gynaecol. 2017; 40: 68-81. https://doi:10.1016/j.bpobgyn.2016.09.006
Al-Hendy A, Myers ER, Stewart E. Uterine Fibroids: Burden and Unmet Medical Need. Semin Reprod Med. 2017; 35(6): 473-480. https://doi:10.1055/s-0037-1607264
Avramenko NV, Barkovskij DYe, Kabachenko OV, Lecin DV. Suchasni poglyadi reproduktologa na etiopatogenez i likuvannya lejomiomi matki. Zaporozhskij medicinskij zhurnal. 2017; 19(3): 381-386. https://doi: 10.14739/2310-1210. 2017.3.100953. [Avramenko NV, Barkowsky DYe, Kabachenko OV, Letsin DV. Reproductologist’s current views on etiopathogenesis and treatment of uterine leiomyoma. Zaporozhye medical journal. 2017; 3(19): 381-386. (In Ukr). https://doi.org/10.14739/2310-1210. 2017.3.100953].
Lisiecki M, Paszkowski M, Wozniak S. Fertility impairment associated with uterine fibroids – a review of literature. Prz Menopauzalny. 2017;16(4):137-140. https://doi:10.5114/pm.2017.72759
Genc M, Genc B, Cengiz H. Adenomyosis and accompanying gynecological pathologies. Arch Gynecol Obstet. 2015; 291(4): 877-881.
https://doi:10.1007/s00404-014-3498-8
Chapron C, Vannuccini S, Santulli P, Abrao MS, Carmona F, Fraser IS, et al. Diagnosing adenomyosis: an integrated clinical and imaging approach. Hum Reprod Update. 2020; 26(3): 392-411. https://doi:10.1093/humupd/dmz049
Naftalin J, Hoo W, Nunes N, Holland T, Mavrelos D, Jurkovic D. Association between ultrasound features of adenomyosis and severity of menstrual pain. Ultrasound Obstet Gynecol. 2016; 47(6): 779-83. https://doi: 10.1002/uog.15798
Mitkov V. V., Huako S. A., Cyganov S. E., Kirillova T. A., Mitkova M. D. Sravnitelnyj analiz dannyh elastografii sdvigovoj volnoj i rezultatov morfologicheskogo issledovaniya tela matki (predvaritelnye rezultaty).
Ultrazvukovaya i funkcion. diagnostika. 2013; 5: 99-114. [Mitkov VV, Khuako SA, Tsyganov SE, Kirillova TA, Mitkova MD Comparative Analysis of Shear Wave Elastography and Results of Uterine Morphological Examination (Preliminary Results). Ultrasound and Functional Diagnostics. 2013; 5: 99114. (In Russ)].
Zhang M, Wasnik AP, Masch WR, Rubin JM, Carlos RC, Quint EH, Maturen KEJ Transvaginal Ultrasound Shear Wave Elastography for the Evaluation of Benign Uterine Pathologies: A Prospective Pilot Study. Ultrasound Med. 2019; 38(1): 149155. https://doi: 10.1002/jum.14676
Guerriero S, Saba L, Pascual MA, Ajossa S, Rodriguez I, Mais V, Alcazar JL. Transvaginal ultrasound vs magnetic resonance imaging for diagnosing deep infiltrating endometriosis: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2018; 51(5): 586595. https://doi:10.1002/uog.18961
Karageyim Karsidag AY, Buyukbayrak EE, Kars B, Unal O, Turan MC. Transvaginal sonography, sonohysterography, and hysteroscopy for investigation of focal intrauterine lesions in women with recurrent postmenopausal bleeding after dilatation & curettage. Arch Gynecol Obstet. 2010; 281(4): 637-643. https://doi:10.1007/s00404–009–1150–9
Wanderley MD, Alvares MM, Vogt MF, Sazaki LM. Accuracy of Transvaginal Ultrasonography, Hysteroscopy and Uterine Curettage in Evaluating Endometrial Pathologies. Rev Bras Ginecol Obstet. 2016; 38(10): 506-511. https://doi: 10.1055/s-0036-1593774
Stoelinga B, Hehenkamp WJ, Brolmann HA, Huirne JA. Real-time elastography for assessment of uterine disorders. Ultrasound Obstet Gynecol. 2014; 43(2): 218-226. https://doi:10.1002/uog.12519
Stoelinga B, Hehenkamp WJK, Nieuwenhuis LL, Conijn MMA, van Waesberghe JHTM, Brolmann HAM, et al. Accuracy and Reproducibility of Sonoelastography for the Assessment of Fibroids and Adenomyosis, with Magnetic Resonance Imaging as Reference Standard. Ultrasound Med Biol. 2018; 44(8): 1654-1663. https://doi:10.1016/j.ultrasmedbio.2018.03.027
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