THE SAFETY OF PHOTOSENSITIZERS AS A PREVENTIVE DRUG FOR INDUSTRIAL POULTRY FARMING
Keywords:photosensitizers, industrial poultry farming, product safety, microbiological assessment, prevention.
The aim of the work was to determine the safety of the use of photosensitizers as a preventive drug for industrial animals.
In the theoretical part, the definition of photosensitizers was given with a description of the reactions in which they enter into biological systems, the purpose of the work and the tasks were formulated.
In the practical part, the effectiveness of the Photoditazine photosensitizer was determined in order to maintain the well-being of the livestock of industrial birds and to obtain high-quality and safe poultry products. In vivo experiments were conducted to determine the effectiveness of photosensitizers as a preventive drug for production animals. Studies were also conducted to determine the safety of products obtained from experimental animals by feeding their meat to laboratory rats with further determination of their pancreatic elastase concentration by ELISA. For the experiments, non-linear white female rats were selected as the most adequate test object for rapid analysis of the safety of raw materials obtained after the use of photosensitizers.
Bondarenko V.M., Konovalova G.N., Nikolaeva E.V. i dr. Effekt fotodinamicheskogo vozdejstviya metallokompleksov proizvodnyh hlorina E6 na uslovno patogennye bakterii s ispolzovaniem sverhyarkih svetodiodov holodnogo belogo sveta. Lazernaya medicina 2008 12(2): 26-30
Gejnic A.V., Sorokatyj A.E., Yagudaev D.M., Truhmanov R.S. Fotodinamicheskaya terapiya. Istoriya sozdaniya metoda i ee mehanizmy
GOST R ISO 20776-1-2010 «Klinicheskie laboratornye issledovaniya i diagnosticheskie test-sistemy in vitro»
GOST R 50396.0-92 «Myaso pticy, subprodukty i polufabrikaty ptichi. Metody otbora prob i podgotovka k mikrobiologicheskim issledovaniyam»
GOST 31468-2012 «Myaso pticy, subprodukty i polufabrikaty iz myasa pticy. Metod vyyavleniya salmonell»
GOST ISO/MEK 17025:2009 (ISO/IEC 17025:2005) «Obshie trebovaniya k kompetentnosti ispytatelnyh i kalibrovochnyh laboratorij»
GOST 10444.15-94 «Produkty pishevye. Metody opredeleniya kolichestva mezofilnyh aerobnyh i fakultativno-anaerobnyh mikroorganizmov»
GOST 28566-90 «Produkty pishevye. Metod vyyavleniya i opredeleniya kolichestva enterokokkov»
GOST 31746-2012 «Produkty pishevye. Metody vyyavleniya i opredeleniya kolichestva koagulazopolozhitelnyh stafilokokkov i Staphylococcus aureus»
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