COMPARISON OF DIAGNOSTIC EFFECTIVENESS OF MAGNETIC RESONANCE IMAGING WITH ASL - PERFUSION OF THE LIVER AND CLINICAL ELASTOGRAPHY IN VIRAL HEPATITIS

Authors

  • E. Simakina Smolensk State Medical University
  • T. Morozova Smolensk State Medical University

Keywords:

ASL – perfusion, magnetic resonance imaging, viral hepatitis

Abstract

Objective. To compare the diagnostic effectiveness of magnetic resonance imaging with ASL – perfusion liver and clinical elastography in viral hepatitis.

Materials and methods. 109 patients with viral hepatitis were examined. All subjects (n=109) underwent abdominal ultrasound with doppler vascular examination and clinical elastography, ASL – perfusion of the liver with magnetic resonance imaging (MRI) with an assessment of the volume of hepatic blood flow (HBF, ml/100g/min).

Results. Moderate correlation of ASL – perfusion of the liver in MRI with clinical elastography and biopsy data was observed in steatosis (r=0.7) and steatohepatitis (r=0.7); strong correlation was observed in hepatitis (r=0.8) and cirrhosis (r=0.9). Diagnostic and prognostic significance of ASL perfusion of the liver in patients with viral hepatitis in the prediction of fibrotic process – AUROC 0.889 (95% CI 0.801-0.903), clinical elastography – AUROC 0.888 (95% CI 0.801-0.915), biopsy – AUROC 0.978 (95% CI 0,974–0,998). 

Conclsion. ASL - perfusion of the liver during MRI in patients with viral hepatitis should be included in the diagnostic algorithm.

Author Biographies

E. Simakina , Smolensk State Medical University

assistant of the department of infectious diseases  with a course of epidemiology

T. Morozova, Smolensk State Medical University

MD Head of the Department of Radiation Diagnostics and Radiation Therapy

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Published

2021-03-22

Issue

Vol. 5 No. 11(63) (2020)

Section

Статьи

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