LEPTIN AND PECULIARITIES OF PUBERTYGENESIS IN ADOLESCENT GIRLS WITH GYNECOLOGICAL PATHOLOGY, BORN LOW OR HIGH TO GESTATIONAL WEIGHT
DOI:
https://doi.org/10.31618/ESSA.2782-1994.2021.2.76.205Keywords:
puberty, leptin, small gestational weight, macrosomiaAbstract
The article outlines the problems of the influence of leptin on the formation of menstrual function in adolescent girls born with low and excessive body weight. The risk factors that are triggers in the formation of gynecological pathology have been identified and indicated. The deviation of body weight in girls at birth is one of the triggers of the pathological course of pubertygenesis, the course of which is accompanied by a clear relationship between the production of leptin(L) and body mass index(BMI), is manifested by impaired physical development, menstrual function and is most often combined with pathological changes in the functioning of the autonomic nervous system, which must be taken into account when verifying diagnosis and treatment of such patients.
References
Wennerström EC, Simonsen J, Melbye M. Long-Term Survival of Individuals Born Small and East European Scientific Journal #12(76), 2021 Large for Gestational Age. PLoS One. 2015 Sep 21;10(9):e0138594. doi: 10.1371/journal.pone.0138594. PMID: 26390219; PMCID: PMC4577072.
Vikström J, Hammar M, Josefsson A, Bladh M, Sydsjö G. Birth characteristics in a clinical sample of women seeking infertility treatment: a case-control study. BMJ Open. 2014 Mar 10;4(3):e004197. doi: 10.1136/bmjopen-2013-004197. PMID: 24613821; PMCID: PMC3963097.
Garces A, Perez W, Harrison MS, Hwang KS, Nolen TL, Goldenberg RL, Patel AB, Hibberd PL, Lokangaka A, Tshefu A, Saleem S, Goudar SS, Derman RJ, Patterson J, Koso-Thomas M, McClure EM, Krebs NF, Hambidge KM. Association of parity with birthweight and neonatal death in five sites: The Global Network's Maternal Newborn Health Registry study. Reprod Health. 2020 Dec 17;17(Suppl 3):182. doi: 10.1186/s12978-020-01025-3. PMID: 33334362; PMCID: PMC7745358.
Ma R, Luo Y, Wang J, Zhou Y, Sun H, Ren X, Xu Q, Zhang L, Zou L. Ten-year time trends in preterm birth during a sociodemographic transition period: a retrospective cohort study in Shenzhen, China. BMJ Open. 2020 Oct 20; 10(10):e037266. doi: 10.1136/bmjopen-2020-037266. PMID: 33082182; PMCID: PMC7577040.
Huraseva A.B. Reproduktivnoe zdorovje zhenshin, rodivshihsya s polyarnymi znacheniyami masy tela: Avtoreferat. dis. d-ra med. nauk: cpec.
01.01«Akusherstvo i ginekologiya» / Huraseva A.B. – Volgograd, 2010. – 10 s.
Nazarenko L.G., Nesterzova N.S. Aspekty reproduktivnogo zdorovja u zhenshin s niskoy i izbytochnoy massoy tela pri rozhdenii. Zdorovje zhenshiny. 2016; № 10: 53-55.
Bogdanova EA. Prakticheskaya ginekologiya molodykh [Practical gynecology of young people]. Moscow: “Medical book”; 2011. P. 238
Rannee i pozdnee poyavlenie pervoy menstruatsii (menarhe) u devochek [Elektronnyiy resurs] // Derzhavna ustanova «Institut ohoroni zdorov’ya dItey ta pIdlItkIv NatsionalnoYi akademIYi medichnih nauk UkraYini». – Rezhim dostupu: http: //iozdp. org.ua/ index.php/2012-09-03-08-35-35
Tuchkina M. Yu. Treatment of adolescent girls with abnormal uterine bleeding taking into account psychoemotional and vegetative status / Tuchkina I. A., Tuchkina M. Yu., Novikova A. A. // Journal of Education, Health and Sport. 2019; 9(5):575-582.eISNN 2391-8306. DOI
http://dx.doi.org/10.5281/zenodo.3239459
Tuchkina I. Disorders of menstrual function in adolescents with autonomic dysfunction / Tuchkina I., Tuchkina M., Merenkova I., Gnatenko O., Dobrovolskaya L. // Abstract book of the 19- th World Congress of PAG, 2020, P-105, p.34
Korrektsiya narusheniy vegetativnoy nervnoy sistemyi u podrostkov s ginekologicheskoy patologiey/ M.Yu.Tuchkina// Materiali Vseukrayinska naukovopraktichna konferentsiya «Aktualni pitannya akusherstva, ginekologiyi I reproduktivnoyi meditsini» 20 zhovtnya 2017 roku, m. Zaporizhzhya, st. 24 - 25
Tuchkina I.A., Dobrovolskaya L.A., Tuchkina M.Yu. Kliniko-diagnosticheskie aspektyi pervichnoy dismenorei v podroskovom vozraste // Medicine (Almaty). – 2016. – No 6 (168). – R. 51-56.
I. Tuchkina, L. Vygovskaya, A. Novikova. Features of uterine blood flow in adolescents with abnormal uterine bleeding of puberty. J Clin Med Kaz. 2019; 4(54):21-24
Tuchkina I.O., L.A. Dobrovolska, L.A.VigIvska, M.Yu TuchkIna / SposIb lIkuvannya dismenoreYi u dIvchat-pIdlItkIv // Patent na korisnu model #94513U opubl.10.11.2015, dIE z
11.2015,UkraYina. Z. № u201408487 vId 25.07.2014. Zayavnik ta patentovlasnik HNMU.
Zatrimka rostu vnutrishnoutrobnogo ploda : metodichnI vkazIvki dlya likariv-interniv, likarIv akusheriv-ginekologiv, dityachih ginekologiv, pediatriv, simeynih likariv / uporyadniki : I. O. Tuchkina, L. A. Vygovska, G. V. Maltsev [ta in.]. – Kharkiv : HNMU, 2018. – 40 s.
Danilenko G.N., Shvets A.N., Shvets Yu.N. Fizicheskoe razvitie harkovskih podrostkov v dinamike za 30 let // SMB. 2017. №1 (59). URL: https://cyberleninka.ru/article/n/fizicheskoe-razvitieharkovskih-podrostkov-v-dinamike-za-30-let (data obrascheniya: 11.01.2022)
Bogdanova, E. A. Morfofunktsionalnaya i somatotipologicheskaya harakteristika shkolnikov Respubliki Kalmyikiya: avtoref. dis. ... kand. biol.nauk. / E.A Bogdanova. – Astrahan, 2010. – 26 s.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
CC BY-ND
A work licensed in this way allows the following:
1. The freedom to use and perform the work: The licensee must be allowed to make any use, private or public, of the work.
2. The freedom to study the work and apply the information: The licensee must be allowed to examine the work and to use the knowledge gained from the work in any way. The license may not, for example, restrict "reverse engineering."
2. The freedom to redistribute copies: Copies may be sold, swapped or given away for free, in the same form as the original.