APPLICATION OF SPECT EXAMINATION WITH 99MTC MDP IN DENTAL IMPLANTOLOGY
DOI:
https://doi.org/10.31618/ESSA.2782-1994.2021.2.76.207Keywords:
SPECT, 99mTc MDP, dental implants, osseointegration, boneAbstract
Treatment with intraosseous osteointegrable dental implants is a modern therapeutic method that achieves complete rehabilitation by fully restoring the patient's masticatory function and aesthetics. The success of their application is closely related to the process of osseointegration. Osteointegration is the process of bone formation between the alloplastic material and the surrounding biological environment. The quality and quantity of bone available is a major prognostic factor for the success of dental implants. Some authors evaluate metabolic activity of bone after placement of dental implants or bone grafts using conventional scintigraphy and singlephoton emission computed tomography (SPECT). The aim of the publication is to present the application of the SPECT study with 99mTc MDP in dental implantology.
References
Hadzhijska – Popova V. Prilozhenie na nuklearnomedicinskite metodi za diagnoza naurolitiazata i nejnite uslozhnenija. Disertacija, MU-Sofija, 2013
Abrahamsson I., Linder E., Lang N.P. Implant stability in relation to osseointegration: an experimental study in the Labrador dog. Clin Oral Implants Res. 2009;20(3):313–318
Ackerhalt, R.E., Blau, M., Bakshi, S. &Sondei, J.A. A comparative study of three 99mTClabelled phosphorus com-pounds and 18F-fluoride for skeletal imaging. Journal of Nuclear Medicine, 1974, 15: 1153-1157
Albrektsson T, Johansson C. Osteoinduction, osteoconduction and osseointegration. Eur Spine J 2001; 10(suppl 2): S96–S101
Alberto PL. Implant reconstruction of the jaws and craniofacial skeleton. Mt Sinai J Med 1998; 65:316-21
Alberto R. Overview of current labelling methods. TECHNETIUM-99m RADIOPHARMACEUTICALS: STATUS AND TRENDS. INTERNATIONAL ATOMIC ENERGY AGENCY. VIENNA, 2009, 19-40
Alberts K, Dahlborn M, Hindmarsh J, Ringertz H, Sonderborg B. Radionuclide scintimetry for diagnosis of complications following femoral neck fracture. Acta Orthop Scand 1984; 55:606-611
Bailey DL., Humm JL., Todd-Pokropek A., van Aswegen A. Nuclear Medicine Physics: A Handbook for Teachers and Students. International atomic energy agency. Vienna, 2014
Bambini F, Memè L, Procaccini M, Rossi B, Lo Muzio L. Bone scintigraphy and SPECT in the evaluation of the osseointegrative response to immediate prosthetic loading of endosseous implants: a pilot study. Int J Oral Maxillofac Implants. 2004 Jan-Feb;19(1):80-6
Berding, G., Bothe, K.J., Gratz, K.F., Schmelzeisen, R., Neu- kam, F.W. & Hundeshagen, H. Bone scintigraphy in the evaluation of bone grafts used for mandibular reconstruction. European Journal of Nuclear Medidine, 1994, 21: 113- 117
Berggren, A., Weiland, A.J. & Ostrup, L.T. Bone scintigraphy in evaluating the viability of composite bone grafts re-vascularized by microvascular anastomoses, conventional autogenous bone grafts, and free non-revascularized periosteal grafts. Journal of Bone and Joint Surgery, 1982, 64: 799- 809
Bergstedt, H.F., Korlof, B„ Lind, M.G. & Wersall, J. Scintigraphy of human autologous rib transplants to a partially resected mandible. Scandinavian Journal of Plastic and Reconstructive Surgery, 1978, 12: 151-156
Bhandari SK, Mondal A. Role of single photon emission computerised tomography in evaluating osseointegration of indigenous DRDO implants: An in vivo study. Med J Armed Forces India. 2016 Jan;72(1):48-53
Bothe, K.J., Neukam, F.W. & Reilmann, L. Knochensz- intigraphie bei Auflagerungsosteoplastiken in Kombination mit Branemark-Implantaten. Zeitschrift fur Zahnarztliche Implantologie, 1992, 8: 30-35
Bragger U, Burgin W, Lang NP, Baser D. Digital subtraction radiography for the assessment of changes in peri-implant bone density. Int J Oral Maxillofac Implants 1991;6:160-6
Cervelli V, Cipriani C, Migliano E, Giudiceandrea F, Cervelli G, Grimaldi M. SPECT in the long-term evaluation of osteointegration in intraoral and extraoral implantology. J Craniofac Surg 1997;8:379–382
Chaushev, B.; Micheva, I.; Bochev, P.; Dancheva, J.; Yordanova, C.; Klisarova, A.; Krasnaliev, I. Diagnostic accuracy of 18FFDGPET/CT in detection of bone lesions in patients with Multiple Myeloma. European Journal of Nuclear Medicine and Molecular Imaging. 2016;43:S319-S319
Cochran DL, Nummikoski PV, Higginbottom FL, Hermann JS, Makins SR, Buser D. Evaluation of an endosseous titanium implant with a sandblasted and acid-etched surface in the canine mandible: Radiographic results. Clin Oral Implants Res 1996;7:240–252
Coggle JE. Effetti biologici delle radiazioni. Torino, Italy: Ed. Minerva Medica, 1998
de Jonge, F.A.A., Pauwels, E.K.J. Technetium, the missing element. Eur J Nucl Med, 1996, 23, 336–344
Delloye, C, de Nayer, P., Allington, N., Munting, E., Coutellier, L. & Vincent, A. Massive bone allografts in large skeletal defects after tumor surgery: a clinical and microrad- iographic evaluation. Archives of Orthopedic and Trauma Surgery, 1988, 107: 31—41
Ell P.J., Khan O., Jarrit P.J., Cullum I.D. Chapman and Hall; London: Radionuclide Section Scanning – an Atlas of Clinical Cases. Chapter 3, Clinical Results. 1982, 45–60
Fleming, W.H., Mcllraith, J.D. & King, E.R. Photoscanning of bone lesions utilising strontium-85. Radiology, 1961, 77: 635-636
Francis, M.D., Fogelman, I. 99mТс diphosphonate uptake mechanism in bone. In Fogelman, I., ed. Bone Scanning in Clinical Practice., 1987, Pp. 7-17. Springer: London, Berlin, Heidelberg
Gahlert M., Röhling S., Wieland M., Sprecher C.M., Kniha H., Milz S. Osseointegration of zirconia and titanium dental implants: a histological and histomorphometrical study in the maxilla of pigs. Clin Oral Implants Res. 2009;20(11):1247–1253
Galasko CS. Proceedings: the pathological basis for skeletalscintigraphy. Br J Radiology 1975;48:72-6
Greenberg, B.M., Jupiter, J.B., McKusick, K. & May, J.W. Correlation of postoperative bone scintigraphy with healing of vascularized fibula transfer: A clinical study. An¬nals of Plastic Surgery, 1989, 23: 147-154
Hutton BF. The origins of SPECT and SPECT/CT. Eur J Nucl Med Mol Imaging. 2014 May;41 Suppl 1:S3-16
Jaffin RA, Kumar A, Berman CL. Immediate loading of implants in partially and fully edentulous jaws: A series of 27 case reports. J Periodontol 2000;71:833–838
Jamil M.U., Schliephake H., Berding G. Prosthetic scintigraphic study of healing of implants combined with bone transplantation in extreme atrophy and after tumor resection. Mund Kiefer Gesichtschir. 1999;3:35–39
Kelly, J.F., Cagle, J.D., Stevenson, J.S. & Adler, GJ. Technetium-99m radionuclide bone imaging for evaluating mandibular osseous grafts. Journal of Oral Surgery, 1975, 33: 11- 17
Khan O. Radioisotope section scanning. Cancer Res. 1980;40:3059–3064
Khan O. Emission and transmission computed tomography in the detection of space occupying disease of the liver. BMJ. 1981;283:1212–1214
Khan O., Archibald A, Thomson E. The role of quantitative single photon emission computerized tomography (SPECT) in the osseous integration process of dental implants. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90(2):228–232
Khang W, Feldman S, Hawley CE, Gunsolley J. A multicenter study comparing dual acid-etched and machined-surfaced implants in various bone qualities. J Periodontol 2001; 72:1384–1390
Krasnow AZ, Collier BD, Kneeland JB, Carrera GF, Ryan DE, Gingrass D, Sewall S, Hellman RS, Isitman AT, Froncisz W, et al. Comparison of highresolution MRI and SPECT bone scintigraphy for noninvasive imaging of the temporomandibular joint. J Nucl Med. 1987 Aug;28(8):1268-74
Linkow L, Rinaldi A. The significance of "fibro-osseous integration" and "osseointegration" in endosseous dental implants. Int J Oral Implant 1987; 2:41-46
Ludwig Catherine, Chicherio Christian, Terraneo Luc. Functional imaging studies of cognition using 99mTc-HMPAO SPECT: empirical validation using the n-back working memory paradigm. Eur J Nucl Med Mol Imaging. 2008;35(4):695–703
Lukash FN, Tenenbaum NS, Moskowitz G. Long-term fate of the vascularized iliac crest bone graft for mandibular reconstruction. Am J Surg. 1990 Oct;160(4):399-401
Mayfielf L, Skoglung A, Nobreus Ashram R. Clinical radiographic evaluation following a delivery of fixed reconstructions of GBR treated titanium fixtures. Clin Oral Implants Res 1998;9:292-302
Meidan Z., Weisman S., Baron J., Binderman I. Technetium 99m-MDP scintigraphy of patients undergoing implant prosthetic procedures: a follow up study. J Periodontol. 1994 April;65(4):330–335
Meijer H.J.A., Steen W.H.A., Bosman F. A comparison of methods to assess marginal bone height around endosseous implants. J Clin Periodontol. 1993;20:250–253
Merrick MV. Essentials of Nuclear Medicine. Edinburgh: Churchill Livingstone, 1984
Misch Carl E. Contemporary Implant Dentistry. 2nd ed. Mosby; 1999. The implant quality scale: a clinical assessment of the health-disease continuum; pp. 21–32
Mustafa K, Wennerberg A, Wroblewski J, Hultenby K, Lopez BS, Arvidson K. Determining optimal surface roughness of TiO(2) blasted titanium implant material for attachment, proliferation and differentiation of cells derived from human mandibular alveolar bone. Clin Oral Implants Res 2001; 12:515–525
Persson LG, Berglundh T, Lindhe J, Sennerby L. Re-osseointegration after treatment of periimplantitis at different implant surfaces. An experimental study in the dog. Clin Oral Implants Res 2001;12:595–603
Roccuzzo M, Bunino M, Prioglio F, Bianchi SD. Early loading of sandblasted and acid-etched (SLA) implants: A prospective split-mouth comparative study. Clin Oral Implants Res 2001;12:572–578
Schliephake H, Berding G, Neukam FW, Bothe KJ, Gratz KF, Hundeshagen H. Use of sequential bone scintigraphy for monitoring onlay grafts to grossly atrophic jaws. Dentomaxillofac Radiol. 1997 Mar;26(2):117-24
Schliephake H., Berding G. Evaluation of bone healing in patients with bone grafts and endosseous implants using SPECT. Clin Oral Implants Res. 1998;9(1):34–42
Sharpe PF, Gemmell H, Smith SF. Medicina nucleare. Roma, Italy: CIC Edizioni Internazionali, 2000
Shibli Jamil Awad, Grassi Sauro, Cristina de Figueiredo Luciene. Influence of implant surface topography on early osseointegration: a histological study in human jaws. J Biomed Mat Res Part B Appl Biomat. 2007;80(2):377–385
Snorrason F, Karrholm J, Lowenhielm G, Hietala S, Hansson L. Poor fixation of the Mittelmeier hip prosthesis. Acta Orthop Scand 1989; 60:81-85
Stevenson, J.S., Bright, R.W., Dunson, G.L. & Nelson, F.R. Technetium-99m phosphate bone imaging: A method for assessing bone graft healing. Radiology, 1974, 110: 391-394
Stromqvist B, Hansson L, Nilson L, Thorngren K. Prognostic pre¬cision postoperative Tc99m-MDP scintimetry after femoral neck fracture. Acta Orthop Scand 1987; 58:494-198
Subramanian, G. & McAfee, J.G. A new complex of 99mTc for skeletal imaging. Radiology, 1971, 99: 192-196
Trisi P, Rao W, Rebaudi A. A histometric comparison of smooth and rough titanium implants in human low-density jawbone. Int J Oral Maxillofac Implants 1999;14:689–698
Utz J, Lull R, Galvin E. Asymptomatic total hip prosthesis: Natural history determined using Tc-99m-MDP bone scans. Radiology 1986; 161:509-5112
van der Stelt PF. Computer assisted interpretation in radiographic diagnosis. Dent Clin N Am 1993;37:683-6
Wahl G. Postoperative Knochenstoffwechselaktivitaten und ihre bedeutung bei der belastung von implanten. Zahnarztl Impiantai 1986; 2:140-144
Wilson, BG. "The evolution of PET-CT." Radiologic Technology 76, no. 4 (2005): 301
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
CC BY-ND
A work licensed in this way allows the following:
1. The freedom to use and perform the work: The licensee must be allowed to make any use, private or public, of the work.
2. The freedom to study the work and apply the information: The licensee must be allowed to examine the work and to use the knowledge gained from the work in any way. The license may not, for example, restrict "reverse engineering."
2. The freedom to redistribute copies: Copies may be sold, swapped or given away for free, in the same form as the original.
